Adeline Siew, PhD

Technology improvements in analytical testing tools have helped increase understanding of molecules and speed up development processes.

Safe and effective drug targeting with ADCs requires careful selection of drug, antibody, and linker. 

Safe and effective drug targeting with ADCs requires careful selection of drug, antibody, and linker.

The new label-free method for quantifying intracellular bioavailability can be used to predict drug exposure to target cells and hence its efficacy.

Industry experts discuss how advances in analytical testing tools have helped address challenges in pharmaceutical analysis.

Pharmaceutical Technology marks 40 years of publishing.

Industry experts discuss best practices for dissolution testing of poorly soluble, immediate-release, and controlled-release formulations and the different analytical approaches used.

Transdermal and inhaled/nasal delivery provide alternative routes of administration for macromolecules.

Design of experiment plays a crucial role in the optimization process of formulation development.

David Fulper, PhD, director of technology support at Catalent, shares insights on the challenges and opportunities for cannabis-based therapeutics.

Capsule filling is a complex process, and the product to be encapsulated must be well developed to ensure mass uniformity.

Principles of dissolution testing, including method development and testing apparatus, are reviewed.

A dissolution method should have adequate discriminatory power to detect formulation changes that affect the dissolution rate of a drug product.

The proliferation of counterfeit medicines is nothing new to pharma; however, the scale of the problem seems to be escalating.

Contract service providers stay competitive by increasing the capacity and efficiency of their manufacturing activities.

Excipients play a crucial role in the manufacturing of solid-dosage forms and the performance of the finished drug product.

Pricing of a lifesaving allergy treatment raises concerns.

Sound process understanding and having effective controls in place are crucial in ensuring that consistent product quality is obtained during API manufacturing.

Industry experts discuss key considerations in the development of orally disintegrating tablets.

Polymers have played a key role as solubilizing excipients. Industry experts explain why polymer structures and functionalities are important considerations in formulation development.

Lipid-based drug delivery is increasingly being used to tackle oral bioavailability challenges resulting from poor solubility.

Aseptic spray drying provides an alternative to lyophilization as an enabling stabilization technology for parenteral biologic formulations.

Experts discuss the key considerations in the development of an autoinjector.

Pharma has voiced strong opposition against Britain’s departure from the EU.

Armin Gerhardt, associate professor of Pharmaceutical Science, Concordia University Wisconsin School of Pharmacy, discusses the effects of moisture on product quality and how to achieve good control of moisture during pharmaceutical manufacturing operations.

Pharma understands the importance of patient centricity, but the problem is the gap between intent and action.

Choosing the right container and container closure system is crucial for ensuring product quality, safety, and efficacy of a biologic formulation.

Pharma has huge responsibilities resting on its shoulders to deliver safe and effective medicine.

The reporter bioassay, used to evaluate ADCC activity of therapeutic antibodies, complements the classical ADCC assay.

Liquid formulations in hard-shell capsules or softgels are becoming a popular option for HPAPIs because of advantages such as improved safety and lower risk of potential exposure and product cross contamination.