Manufacturing

Jennifer Markarian is manufacturing editor of BioPharm International.

Articles

Advances in automation and cleanroom technology improve efficiency for small commercial quantities of aseptically filled drug products.  

Filling Small Batches

Aseptic spray drying offers a technology alternative to manufacture thermally stable vaccines.

Breaking the Cold Chain for Vaccines

Beth Totin is chief commercial officer, ApiJect Systems, Corp.

Marcus Webb is director of communications, ApiJect Systems, Corp.

Blow-fill-seal (BFS) technology presents an economical option for single-unit dose delivery of vaccines. 

Reducing Packaging Costs for Prefilled Syringes

The semi-automated TipFil Syringe Filler from TurboFil Packaging Machines provides accurate and consistent fills. 

Benchtop Syringe Filler for Drug Compounding

ILC Dover’s soloPure flexible aseptic isolator creates a closed environment for sterile filling. 

Single-Use Isolator Chamber for Sterile Manufacturing

Richard Denk is Head Sales Containment at SKAN AG, www.skan.ch, Richard.Denk@skan.ch.

Decontamination, automation, and containment are important considerations
for aseptic manufacturing in isolators.


Understanding the Impact of Annex 1 on Isolator Operation

The expanded agreement will include aseptic fill/finish services at its San Diego, CA facility.

Aji Bio-Pharma Expands Agreement with AstraZeneca to Include Drug Product Manufacturing

Anne Marie Dixon-Heathman  is the owner and president of Cleanroom Management Associates, Inc.

Traditional methods of testing cleanroom garments fail to test for dynamic conditions in the cleanroom. A holistic approach considers particulate shedding and heat load during processing, as well as the impact of laundering on garment life cycle. 


A Real-World Approach to Evaluating Cleanroom Garments

The GENiSYS R from AST (pictured) is a modular system that automates aseptic filling and the closing of vials, syringes, and cartridges.

Robotic Modular System for Small Batch Filling

Feliza Mirasol is the science editor for 

CDMOs address the unique challenges of liquid and lyophilized forms as well as preparing for the large capacity needed for COVID-19 vaccines.

Aseptic/Sterile Processing