Formulation and Drug Delivery, Solid Dosage

Formulating Tablets Layer by Layer

July 03, 2021

Bi-layer tablets are an under-utilized option that can be employed to help reduce treatment burden, but their formulation is more complex than for conventional monolayer products.

Lab-Scale Capsule Filler Provides Flexibility for Dosing Small Quantities

June 10, 2021

New features of Syntegon’s GKF 60 capsule filler include a piezo dosing system, an Automated Process Development tool, and quick changeover to containment.

Moving Beyond Particle Size Control

June 03, 2021

Particle engineering is a vital tool in overcoming many formulation challenges, and technological advances are enabling developers to achieve the full potential of pipeline molecules.

Reviewing Recent Bioavailability Research

March 03, 2021

Various strategies to improve bioavailability are being continuously evaluated, affording greater commercial prospects for the future.

Glatt and Aprecia Collaborate on 3D-Printing for Solid-Dosage Drugs

February 23, 2021

Aprecia's compression-free 3DP manufacturing platform and Glatt’s multiparticulate technologies offer solutions to pharmaceutical dosage design challenges.

Improving Solubility with Amorphous Solid Dispersions

November 03, 2020

Amorphous solid dispersions are a useful tool in overcoming solubility issues, but they have not yet reached full potential in commercial success.

Evonik Launches New Ready-To-Use Powder Premix Blend

October 27, 2020

The new premix can be used with tablets and a range of other solid oral dosage forms.

Masking Taste: A Key Attribute to Success

October 03, 2020

Taste-masking can be of significant importance in ensuring success of a drug product, particularly those targeted to pediatric or geriatric populations.

Capsule Innovations: Speeding Up Drug Development

September 03, 2020

Tight development timelines and accelerated approval pathways favor simple, cost-effective capsule formulations.

Fabrication Modulation of Zein-based Fibers for Oral Delivery of Hydrochlorothiazide

August 03, 2020

This study suggests that using a simple centrifugal method can produce a natural polymer-blend molecule that can successfully be used as an oral delivery mechanism for poorly soluble drugs.