Inhalation Drugs

The authors discuss the analysis of the resulting data, focusing on methods for the calculation of mass median aerodynamic diameter, one of the metrics routinely used for comparative testing.

The author reviews key considerations for formulating powders for use in inhalers. This article is part of a special Drug Delivery issue.

Although there are no regulatory requirements or established pharmacopoeial techniques for the dissolution testing of inhaled drugs, such testing can potentially open up the opportunity to tailor formulation properties.

The pharmaceutical industry?s increasing interest in inhaled drugs has prompted several researchers to propose standard dissolution-testing methods for these products.

After several years of debate and review, the US Food and Drug Administration is calling for the removal of metered-dose inhalers.

Mark Copley discusses the methods used for DPI testing and the challenges presented by the current regulatory framework.

An inhaler mouthpiece that optimizes drug delivery to the lungs and reduces the amount of wasted medication has been developed by US researchers.

Formoterol presents formulators and manufacturers in the asthma and chronic obstructive pulmonary disease marketplace many challenges.

What makes a drug ripe for respiratory delivery?

Scientists at the University of North Carolina at Chapel Hill have successfully tested a new inhaled tuberculosis (TB) vaccine.

A new active dry powder inhaler has been developed using vibration frequencies to aerosolize powders.

New research has led to significant advances in formulations and inhalation systems for pulmonary delivery.

A knowledgeable and experienced contract service provider can help in the development and success of an inhalation drug product.

Recent advances in pressurized metered-dose inhalers provide an optimistic outlook for the treatment of pulmonary and systemic diseases.