Manufacturing

Tornado Spectral Systems, winner of the 2018 CPhI Excellence in Pharma Award for Analysis, Testing, and Quality Control, discusses real-time process measurement for biopharmaceutical and small-molecule drug manufacturing.

The new reagents are designed to support clinical-phase and commercialization stages of cell and gene therapy production and to enhance DNA transfection.

Process architects for pharmaceutical manufacturing facilities must understand cGMPs and how to optimize a design for equipment, processes, and people.

Active and intelligent packaging technologies benefit brand owners, caregivers, and patients.

Requirements for virus filtration must be considered in developing continuous downstream processes.

Charles Ross & Son Company has made improvements to the dual-post hydraulic lift and seal design of its 1500-gallon Multi-Shaft Mixer Model PVM-1500.

Fluid Air’s portable PolarDry Electrostatic Spray Dryer Model 0.1 is compact in size while retaining the same features of previous spray dryers.

GEMÜ’s 1205 electrical position indicator is suitable for demanding applications in category 2, zone 1, and/or zone 21 ATEX areas, as well as for robust use at low temperatures down to -20 °C.

Shortages of life-saving drugs are a regulatory and industry concern. Proper process development may help to ensure drug supply.

While pharma is proving its capabilities to develop novel therapies, the industry still needs to work on manufacturing innovation.

Keeping valuable employees happy-and on the job-may test bio/pharma business decisions.

Intellectual challenge, work/life balance, compensation, and an unclear business outlook create uncertainty among European bio/pharma employees.

Pharmapack Europe expects further increases in innovation across packaging and drug delivery to mirror overall industry trends.

The STERIS ProKlenz ONE alkaline cleaner now has a label performance claim for biofilm removal, in addition to the product’s existing label as a disinfectant and virucide.

Nanoform has unveiled its plans to construct a GMP manufacturing plant that will provide API ‘solution to particle’ nanoization for clinical trials

Capital Recovery Group, Federal Equipment Company, Heritage Global Partners, and PPL Group purchased a 110-acre campus with a flexible pharmaceutical manufacturing and packaging facility from a generics manufacturer in Huntsville, AL.

A new facility in California will expand Orchard Therapeutic’s capacity to develop and deliver lentiviral vector and gene-corrected hematopoetic stem cells.

TrendMiner 2018.R2 software for analysis of time-series data includes the ContextHub platform for expanded, self-service analytics capabilities.

AqVida, winner of the 2018 CPhI Excellence in Pharma Award for manufacturing technology and equipment, identifies advantages of robotics compared to conventional automation in fill/finish operations.

The SafeGuard Preventative Maintenance Solution from PSG’s Griswold provides remote monitoring for a centrifugal pump and its motor.

The Gold Cone X-Flo Filter Cartridge from Camfil APC stays cleaner and lasts longer than conventional pleated filters.

The company is investing approximately $14 million to expand biologics packaging capabilities and capacity at its biologics manufacturing facility in Bloomington, IN.

The company will use GE Healthcare’s off-the-shelf KUBio biologics factory, which is expected to start operations in 2020, to provide development and manufacturing for early- to late-clinical and early-commercial manufacturing stages.

Integration of two separate chromatography data systems boosts workflow efficiency.

Boehringer Ingelheim plans to develop and test new strategies at its Solids Launch facility.

Transdermal patch design, materials, and manufacturing variables, as well as drug formulation and interactions between the API and the adhesive, can affect adhesion and drug delivery.

Virpax’s Patch-in-a-Can technology delivers pain medication using a metered-dose spray film.

To improve production in pharmaceutical manufacturing, the IT, OT, and Quality functional groups must work together to get the most value from existing plant data.

Drug and adhesive formulation are crucial to the development of microneedle patches for pharmaceutical transdermal delivery systems.

Microbial identity data can be critical for determining contamination sources.