Manufacturing

Articles

Two FDA-funded projects at RCPE will look at real-time monitoring and control of drug tablet coating and developing a digital twin for drug production control.

RCPE Awarded FDA Funding to Develop Next-Generation Technology

Edge-AI technology will enable Industry 4.0 automation in pharmaceutical manufacturing.

Neurala Partners with IMA Group on AI for Manufacturing Automation

Automation, digitalization, and supply-chain strategies help mitigate vulnerabilities in both autologous and allogeneic cell therapy manufacturing.

Navigating Cell Therapy Manufacturing Amid Pandemic Woes

Jennifer Markarian is manufacturing editor of BioPharm International.

Automation and tools for remote monitoring are finding increased use as pharmaceutical manufacturing adapts to pandemic restrictions. 

Pandemic Drives Digitalization in Bio/Pharma Manufacturing

Agnes Shanley is senior editor of Pharmaceutical Technology.

Even though many companies are at early stages of digital automation, more are evaluating BioPharma 4.0 tools and leveraging built-in automation to speed scale-up and boost efficiency. 

Skipping Steps to BioPharma 4.0 

Real-time monitoring and the principles of quality by design were used to optimize an OSD coating process.

Using Industry 4.0 to Optimize Oral Solid Dosage Form Manufacturing

Honeywell Forge Cybersecurity Suite’s improved industrial-grade remote access and added protection and risk monitoring aids remote operations.

New Cybersecurity Features Protect Facilities with Remote Operations

Lisa Graham leads the analytics engineering team at Seeq Corporation. She holds a Ph.D. in chemical engineering and is a registered professional chemical engineer. With 20 years of experience across many industries, her technical strengths include chemical engineering, product development and process model development. She has a well-developed acumen in crafting process analytical technology and data analytics solutions to help drive innovation and growth while reducing costs.

Advanced analytics streamlines continuous manufacturing by providing improved insights to data.


Advanced Analytics Delivers Continuous Manufacturing Innovation

Ori Biotech is partnering with manufacturers and materials suppliers to develop an automated system for cell and gene therapy manufacturing. 

Ori Biotech and CellGenix Collaborate on Closed-system, Cell and Gene Therapy Manufacturing

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Ensuring the quality of data in process monitoring and control systems starts in process development phases. 

Building Data Quality In Generates Quality Data OutEnsuring the quality of data in process monitoring and control systems starts in process development phases.

MilliporeSigma’s Bio4C Software Suite combines process control, analytics, and plant-level automation.

Data Visualization and Analysis Software Enables Real-Time Manufacturing Intelligence

Jennifer Markarian is manufacturing editor of Pharmaceutical Technology.

Analyzing process and equipment data provides insights that can improve quality and productivity of pharmaceutical manufacturing.

Analytics Boosts Manufacturing Capabilities

Joseph Reckamp is an analytics engineer at Seeq Corp., where he specializes in pharmaceutical applications. He received BS and MS degrees in chemical engineering from Villanova University and has worked at companies that include GlaxoSmithKline and Evonik.

Advanced analytics and modeling can be used to predict downstream failures, allowing for corrective action before batches are lost. 


Using Online Transition Analysis to Predict Chromatography Column Failure

Enhancements to Augury’s AI-based machine health platform include new capabilities and collaboration tools for personnel working remotely.

Augury Adds Capabilities to Machine Health Platform

Energy and water waste can be improved with new technologies, and sustainability can be considered in the design of new facilities.

Improving Efficiency for Sustainable Pharmaceutical Facilities

Kai Vogt is senior vice-president Corporate Development, Legal and Compliance, Information Technology at Vetter Pharma. 

CDMOs must consider challenges associated with the complexity of contract pharmaceutical manufacturing when approaching digitalization projects. 

Digitalization: A CDMO’s Perspective

Data collected through the Industrial Internet of Things enable predictive maintenance.

Optimizing Machine Health

Chris O’Callaghan is senior product manager at Innopharma Technology, Dublin, Ireland, ocallaghanc@innopharmalabs.com.

Ian Jones, PhD, is founder and CEO of Innopharma Technology and Innopharma College of Applied Sciences, Dublin

Caroline McCormack  is process laboratory manager at Innopharma Technology, Dublin, Ireland.

Luke Kiernan is a PhD student at the Technological University Dublin in Ireland.

Gavin Walker, PhD, is professor and director of the Synthesis and Solid State Pharmaceutical Centre at the University of Limerick in Ireland.

Gareth Clarke is Multieye Product Manager, Innopharma Technology, Dublin,Ireland

Advanced dynamic process control of a fluid-bed granulation process using PAT data improves product quality.

Self-Guided Control of a Fluid Bed Granulation Process

Sartorius and the German Research Center for Artificial Intelligence have established a research laboratory for AI in the biopharmaceutical industry.

Sartorius and German Research Center Collaborate on Artificial Intelligence

Predictive and prescriptive maintenance improve pharmaceutical manufacturing equipment effectiveness. 

Process Control, Automation, and PAT