BioClosure System Reduces Assembly Time

March 30, 2016
Pharmaceutical Technology Editors

AdvantaPure’s BioClosure container closures are intended to save time and money on inventoried parts, assembly, and cleaning validations.

The BioClosure container closures from AdvantaPure are standard, ready-to-use, closed systems. The closures feature elastomeric seals against the containers, and they allow unobstructed fluid paths. Applications include aseptic sampling, cell growth, filling, process R&D, and cold storage.

BioClosure System Assemblies include Single-Use AdvantaFlex fluid transfer tubing and molded container closures, plus filters and caps for media bottles, Erlenmeyer flasks, and carboys. The assemblies, offered in standardized configurations, are intended to save time and money on inventoried parts, assembly, and cleaning validations.

Other key features of the closed system assemblies include:

  • Meet ISO and USP standards including Class VI

  • Made in ISO 7 (Class 10,000) certified clean rooms

  • Easy connections: AdvantaFlex tubing is sterile weldable and heat sealable

  • AdvantaFlex is certified free of animal-derived ingredients

  • Documented quality control: lot traceable with identification on packaging.

Container capacities range from 125 mL to two liters for media bottles, one and two liters for Erlenmeyer flasks, and 2.5 to 40 liters for carboys. Bottle and flask assemblies are provided gamma sterilized. Cap assemblies for carboys are available in two or three port styles and are offered non-sterile or gamma sterilized.

BioClosure System Assemblies are available in platinum-cured, Class VI silicone in addition to AdvantaFlex TPE. The company will showcase the systems at INTERPHEX 2016, in New York NY.

Source: AdvantaPure