Multiple Reaction Monitoring–Mass Spectrometry for Biopharmaceutical Analysis

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Pharmaceutical TechnologyPharmaceutical Technology-07-15-2013
Volume 2013 eBook
Issue 1

The authors describe two applications of a modified mass-spectrometry (MS) method, multiple reaction monitoring (MRM-MS), in biopharmaceutical analysis.

 

The authors describe two applications of a modified mass-spectrometry (MS) method, multiple reaction monitoring (MRM-MS), in biopharmaceutical analysis. The authors determined the relative abundance of process-related proteins and a specific residual impurity by use of an internally standardized MRM-MS technique for a recombinant fusion protein.

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Pharmaceutical Technology’s 2013 Analytical and Bioanalytical Testing ebook

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Articles in this issue
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Impurity Profiling Using Convergence Chromatography and Mass Spectrometry
pt_ebooks_nmr.jpg
Multiple Reaction Monitoring–Mass Spectrometry for Biopharmaceutical Analysis
pt_ebooks_lcms.jpg
Simultaneous Quantitative and Qualitative Measurements in Drug-Metabolism Investigations
pt_ebooks_protein.jpg
Identification and Quantification of Trace-Level Protein Impurities
pt_ebooks_hplc.jpg
Ultra-High-Speed Analysis of Ibuprofen Using HPLC
pt_ebooks_microscopy.jpg
Characterization with Atomic Force Microscopy, Topographic, and 3D Raman
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