Penn Pharma Adds Contained Roller Compaction Equipment in South Wales

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Penn Pharma's equipment addition meets growing need for continuous dry granulation and for handling of highly potent drugs.

Pharmaceutical manufacturer, Penn Pharma, a PCI company, has invested in a contained Gerteis Mini-Pactor for roller compaction of oral solid-dosage drugs containing potent APIs at its Tredegar site in South Wales, the company announced on Mar. 11, 2015.

Roller compaction provides a granulation method for materials that are heat and moisture sensitive, and avoids the use of liquid and high temperatures associated with wet granulation and subsequent drying methods. The Gerteis Mini-Pactor design enhances powder flow and offers effective containment using skan isolator technology and integrated cleaning systems. The process is easily scalable.

"We have recognized and responded to a growing need within the industry for continuous granulation methods by developing our dry granulation capabilities," said Mark Dean-Netscher, vice-president of International Operations at Penn Pharma, in the press release. "This roller compactor can be used from 1-kg development scale up to 100 kg/h at production scale, without the need for additional scale-up work.  This will significantly reduce our clients' costs and allow products to be developed and delivered to market far quicker."

Source: Penn Pharma 

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