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Penn Pharma Adds Contained Roller Compaction Equipment in South Wales

Penn Pharma's equipment addition meets growing need for continuous dry granulation and for handling of highly potent drugs.

Pharmaceutical manufacturer, Penn Pharma, a PCI company, has invested in a contained Gerteis Mini-Pactor for roller compaction of oral solid-dosage drugs containing potent APIs at its Tredegar site in South Wales, the company announced on Mar. 11, 2015.

Roller compaction provides a granulation method for materials that are heat and moisture sensitive, and avoids the use of liquid and high temperatures associated with wet granulation and subsequent drying methods. The Gerteis Mini-Pactor design enhances powder flow and offers effective containment using skan isolator technology and integrated cleaning systems. The process is easily scalable.

"We have recognized and responded to a growing need within the industry for continuous granulation methods by developing our dry granulation capabilities," said Mark Dean-Netscher, vice-president of International Operations at Penn Pharma, in the press release. "This roller compactor can be used from 1-kg development scale up to 100 kg/h at production scale, without the need for additional scale-up work.  This will significantly reduce our clients' costs and allow products to be developed and delivered to market far quicker."

Source: Penn Pharma 

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