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Pharmaceutical Technology

Pharmaceutical Technology-05-15-2015
Volume2015 eBook
Issue 2

Sterilization Effects on Elastomers in Sterile Parenteral Drug Products

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This article looks at data gathered from several studies of a widely marketed chlorobutyl rubber formulation used for vial stoppers and prefilled syringes.

 

This article looks at data gathered from several studies of a widely marketed chlorobutyl rubber formulation used for vial stoppers and prefilled syringes. The studies examined material properties, machinability, function in syringes, and extractables, comparing the use of these sterilization techniques on rubber slabs and prefillable syringe plungers. 

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