WuXi PharmaTech Completes Cell Culture Capacity Expansion
WuXi PharmaTech has completed a cell culture capacity expansion, including two 2000 L disposable bioreactors.
WuXi PharmaTech, a research and development outsourcing company, has completed a cell culture capacity expansion, including two 2000 L disposable bioreactors that are ready for cGMP manufacturing. Previously WuXi AppTec had built a cGMP biologics manufacturing facility with two cell culture suites containing a 500 L and a 1000 L disposable bioreactor. With the expansion, the company operates the largest biologics facility with disposable bioreactors in China and the largest disposable bioreactor in the world, according to a press announcement. WuXi AppTec can now support Phase III clinical manufacturing and initial commercial launch for therapeutic antibody and recombinant protein drugs.
The company also completed the first run of the 2000 L disposable bioreactor using an NS0 mouse myeloma cell line for TaiMed Biologics' ibalizumab, a CD4 entry inhibitor for the treatment of HIV/AIDS infection. WuXi AppTec reproduced in disposable bioreactors a manufacturing process originally implemented in traditional stainless steel bioreactors, with comparable process performance and product quality, the company reports.
Source: WuXi PharmaTech
Drug Solutions Podcast: A Closer Look at mRNA in Oncology and Vaccines
April 30th 2024In this episode fo the Drug Solutions Podcast, etherna’s vice-president of Technology and Innovation, Stefaan De Koker, discusses the merits and challenges of using mRNA as the foundation for therapeutics in oncology as well as for vaccines.
Understanding the Variability in Bioburden Test Results in Biomanufacturing
May 7th 2025This article explores the impact of test volume, microbial distribution, and dilution errors on bioburden testing variability. It presents statistical approaches to estimate percentage error and discusses strategies to optimize microbial enumeration techniques in biopharmaceutical quality control.
Drug Solutions Podcast: Gliding Through the Ins and Outs of the Pharma Supply Chain
November 14th 2023In this episode of the Drug Solutions podcast, Jill Murphy, former editor, speaks with Bourji Mourad, partnership director at ThermoSafe, about the supply chain in the pharmaceutical industry, specifically related to packaging, pharma air freight, and the pressure on suppliers with post-COVID-19 changes on delivery.
Intertek to Expand UK GMP Facility with 6000 Square Feet of Lab and Office Space
May 7th 2025The company said the expansion is in response to globally rising demand for inhaled biologics, which offer distinct advantages in route of administration, but can be challenging products for developers.
