Pharmaceutical Technology-03-02-2014

Pharmaceutical Technology
Outsourcing Outlook

March 02, 2014

Changes in company ownership shake up the CMO industry.

Drug Delivery
Pharmaceutical Technology

March 02, 2014

Despite the progress made in nanomedicine development, there are several issues that remain unresolved. Raj Bawa, PhD, provides insight.

Pharmaceutical Technology
Cover Story

March 02, 2014

Quality-by-design principles enhance a thorough understanding of both product and process technology, which is needed for optimization of solid-dosage manufacturing, including processes for improving solubility, such as hot-melt extrusion, softgels, and liquid-filled capsules.

Pharmaceutical Technology

Manufacturers are taking measures to comply with new package safety rules.

Pharmaceutical Technology

The extended-release performance of drug-loaded pellets manufactured by two methods, drug layering and direct pelletization, was compared.

Pharmaceutical Technology
Product Spotlight

March 02, 2014

7900 ICP-MS Increases Efficiency

Pharmaceutical Technology
Global Feature

March 02, 2014

China's regulatory and compliance environment is set to change as the government declares a crackdown on bribery scandals.

Pharmaceutical Technology
Troubleshooting

March 02, 2014

Bioprocessors should understand the key factors associated with implementing single-use components or platforms, which include materials of construction, components, system design, and vendor support.

Pharmaceutical Technology

In this article, the authors demonstrate that a normal-phase chromatographic method was stability-indicating for a water-sensitive prodrug. The stress conditions using aqueous and non-aqueous conditions were also compared to understand the information obtained with each approach.

Pharmaceutical Technology

Accelerated testing and production create challenges in documenting product quality.

Pharmaceutical Technology
Featured Content

March 02, 2014

Using best practices for manual or automatic inspection can improve the inspection process.

Pharmaceutical Technology
Guest Editorial

March 02, 2014

Conference sessions from PDA and PharmTech expand educational opportunities at INTERPHEX 2014.

Drug Delivery
Pharmaceutical Technology

March 02, 2014

Nanomedicines can offer promising benefits in the diagnosis and treatment of diseases but there are still concerns about the safety and quality of these therapeutics partly because of the lack of clear regulatory guidance. Scott McNeil, PhD, director of the Nanotechnology Characterization Laboratory (NCL), spoke with Pharmaceutical Technology about nanomedicine characterization.

Pharmaceutical Technology

Advances in nanomedicine have provided several potential candidates for safe and effective delivery of siRNA.

Pharmaceutical Technology
Product Spotlight

March 02, 2014

Compact Mass Spectrometer Improves Analysis

Drug Delivery
Pharmaceutical Technology

March 02, 2014

With nanomedicines on the rise, a new class of non-biological complex drugs (NBCDs), which include nanosimilars, has emerged. As drug regulators are faced with the challenge of defining a framework to ensure the safe introduction of the follow-on nano-therapeutics, Stefan Muhlebach explains why NBCDs cannot be assessed using the standard generic or biosimilar approaches.

Pharmaceutical Technology
Product Spotlight

March 02, 2014

ACQUITY QDa Detector Increases Productivity

Pharmaceutical Technology

A survey on postapproval CMC changes was conducted to better understand reporting categories, nature and risks, and review outcomes.

Pharmaceutical Technology

The root cause of drug shortages is mismanagement of variation.

USP evaluates quality attributes for synthetic peptides.

Pharmaceutical Technology

The commercial availability of an increasing diversity of enzymes has led to the growing use of biocatalysts for API synthesis.

Pharmaceutical Technology

SALD-7500nano Expands Measurement of Nanoparticles

Pharmaceutical Technology
Packaging Forum

March 02, 2014

Trends driving pharmaceutical packaging include product protection, productivity boosters, and patient adherence improvement.

Issue PDF
Pharmaceutical Technology

March 02, 2014

Click the title above to open the Pharmaceutical Technology March 2014 issue in an interactive PDF format.