Development

Editor of Pharmaceutical Technology Europe

Articles

Developers need to consider key challenges when approaching accelerated formulation strategies to ensure success.

Successfully Accelerating Formulation Strategies

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Bacteriophages could be crucial weapons in the fight against antibiotic-resistant bacteria.

The State of Phage Therapy 

BioMed X and Boehringer Ingelheim have announced the start of a new research project in brain sensor development. 

BioMed X Institute and Boehringer Ingelheim Start New Research Project in Brain Sensor Development

Yeli Zhang is North America Technical Manager IFF Pharma Solutions, Wilmington, DE.

Elizabeth Tocce is associate application development engineer, Dupont.

Holly Bertrand is Research Investigator IFF Pharma Solutions, Wilmington, DE.

Kevin McIntyre is Laboratory Supervisor, IFF Pharma Solutions, Wilmington, DE.

Fernanda Onofre, Americas Regional Applications Leader, IFF Pharma Solutions, Wilmington, DE.

Amina Faham is Global Director of Applications Development & Innovation; IFF Pharma Solutions, Wilmington, DE.

In this study, researchers evaluated the colloidal microcrystalline cellulose (cMCC) suspending agent—a co-processed material of microcrystalline cellulose and sodium carboxymethyl cellulose (NaCMC)—by using a representative pharmaceutical-grade commercial version of cMCC.

Polymer Influence on the Rheological Properties of Co-Processed Microcrystalline Cellulose and Sodium Carboxymethylcellulose

A key benefit for companies when outsourcing formulation development is the broad experience they can gain from a dedicated service provider, particularly for niche markets.

Gaining Formulation Expertise through Partnerships

Dosage form and patient needs drive excipient choice.

Taste and Appearance: Selecting the Right Excipients 

Poor solubility remains a big issue for drug development and, as such, is driving innovation in approaches and use of novel technologies to help overcome the associated challenges.

Tackling the Big Issue of Solubility

Increased patient-centricity and alternative dosage forms require careful consideration when selecting the best taste-masking approach.

It’s a Matter of Taste-Masking

Investing in formulation strategies earlier on in development will maximize the chance of success.

The Earlier the Better for Formulation Strategies

Alternative drug delivery approaches are promising, but due to their complexity, they need to be sufficiently justified.