Particle Analyzer Based on Light Scattering
The Litesizer 500 from Anton Paar determines particle size, zeta potential, and molecular mass by using light-scattering technology.
The Litesizer 500 from Anton Paar determines the size and stability of nanoparticles and submicroparticles in liquids and how they change with time, pH, temperature and concentration. The instrument determines particle size, zeta potential, and molecular mass by using light-scattering technology, in combination with transmittance measurements.
The user interface is a one-page workflow, where input parameters, results and analysis are on a single page. A measurement series can be set in a few seconds.
Other features include cmPALS, a patented technology that allows the modulator to make large movements, allowing the use of shorter measurements and and lower electric fields, reducing the effects of electrode fouling and deterioration.
Algorithms in the firmware technology allows users to resolve several different particle sizes in a single suspension.
Source: Anton Paar
Understanding the Variability in Bioburden Test Results in Biomanufacturing
May 7th 2025This article explores the impact of test volume, microbial distribution, and dilution errors on bioburden testing variability. It presents statistical approaches to estimate percentage error and discusses strategies to optimize microbial enumeration techniques in biopharmaceutical quality control.
Drug Solutions Podcast: Applying Appropriate Analytics to Drug Development
March 26th 2024In this episode of the Drug Solutions Podcast, Jan Bekker, Vice President of Business Development, Commercial and Technical Operations at BioCina, discusses the latest analytical tools and their applications in the drug development market.
Full Tolerance Coverage Method for Assessing Uniformity of Dosage Units with Large Sample Sizes
March 10th 2025The ‘full tolerance coverage method’ is introduced as a coverage estimation approach for assessing the uniformity of dosage units from large sample sizes, ensuring that no dosage unit exceeds the specification range.
