Particle Analyzer Based on Light Scattering

PTSM: Pharmaceutical Technology Sourcing and Management

PTSM: Pharmaceutical Technology Sourcing and Management-06-07-2016, Volume 11, Issue 6

The Litesizer 500 from Anton Paar determines particle size, zeta potential, and molecular mass by using light-scattering technology.

The Litesizer 500 from Anton Paar determines the size and stability of nanoparticles and submicroparticles in liquids and how they change with time, pH, temperature and concentration. The instrument determines particle size, zeta potential, and molecular mass by using light-scattering technology, in combination with transmittance measurements.

The user interface is a one-page workflow, where input parameters, results and analysis are on a single page. A measurement series can be set in a few seconds.

Other features include cmPALS, a patented technology that allows the modulator to make large movements, allowing the use of shorter measurements and and lower electric fields, reducing the effects of electrode fouling and deterioration.

Algorithms in the firmware technology allows users to resolve several different particle sizes in a single suspension.

Source: Anton Paar