The PPSQ-51A/53A protein sequencers from Shimadzu Scientific Instruments feature the company’s SPD-M30A photodiode array detector.
The PPSQ-51A/53A protein sequencers from Shimadzu Scientific Instruments feature the company’s SPD-M30A photodiode array detector, which has a capillary cell that is 8.5 times longer than standard cells. The detector increases sensitivity and enables the study of longer protein sequences, the company reports.
The protein sequencers separate PTH-amino acids isocratically, providing more stable retention times. Peaks detected in previous cycles can be cancelled using chromatogram subtraction, making it easier for users to identify the correct amino acid. Performing PTH-amino acid analysis in isocratic mode also enables laboratories to reduce liquid waste and running costs through mobile phase recycling.
PPSQ software can be configured to meet a laboratory’s regulated, research and development, or academic needs. The software enables compliance with 21 CFR Part 11 guidelines with regard to security, user management, and audit trail requirements. Data analysis functions allow the reprocessing of chromatograms, the overlaying of multiple chromatograms, chromatogram subtraction, and automatic estimation of amino acid sequences. The sequencers also provide customized reports and yield graph display for a quick and comprehensive view of data.
Source: Shimadzu Scientific Instruments