Sustainability and Stability in Excipients

Raw materials, such as excipients, play an important role in the overall finished drug product. These materials can keep the drug stable, assist in drug delivery in the body, and help with patient adherence. The expansion of the biologics market, according to Peter Freed, head of Global Pharma CTS, Roquette, has made excipient quality even more important to ensure protein integrity and formulation stability.

When it comes to sustainability, Reed points to plant-based excipients, eco-efficient manufacturing, and bio-based circular supply chains as ways to meet performance and environmental targets. Science-based metrics and transparent supply partnerships are also key.

Pharmaceutical Technology® spoke to Freed to find out more about the importance of raw materials in the development and manufacture of pharmaceuticals. Click on the video above to watch the interview.

Roquette will be exhibiting at CPHI Frankfurt in the Excipients zone at stand 8.0P24. CPHI Frankfurt 2025 is being held from Oct. 28–30.

About the speaker

Peter Freed is head of Global Pharma CTS, Roquette.

Transcript

Editor's note: This transcript is a direct, unedited rendering of the original audio/video content. It may contain errors, informal language, or omissions as spoken in the original recording.

Hi, my name is Peter fried. I'm the head of pharma customer Technical Support at Roquette. I lead a group of global scientists that help our customers solve problems, formulate new dosage forms and innovate.

Well, the rise of biologics makes Excipient quality and consistency vital for protein integrity and formulation stability. Therefore traceability and stringent quality control are now essential for compliance and patient safety. Roquettes, proletal mannitol and kleptos, Hydroxypropyl beta cyclodextrin maintain structure and performance throughout manufacturing and storage, so with integrated analytical and formulation expertise, rocket enables a more efficient and scalable development of stable biologics.

The focus on patient experience is driving innovation in taste masking and swallowability. Kleptos and ready like coat highlight how formulation science supports adherence and clean label designalso ethical. Methicel, Aqua coat, ECD coatings enable precision release for optimized outcomes and manufacturing efficiency. And lastly, a growing demand for plant based, sustainable excipients aligned with roquettes bio based innovation strategy.

So Pharma is shifting from cost driven to resilient, flexible supply chains, rockets, global networks strengthened by the qualcaps and IFF pharma solutions integrations ensure a multi regional manufacturing and reduce dependency on individual production sites. Also the company's digital traceability systems enhance visibility from raw materials to finished products. Roquette exemplifies how the sector is building robust future ready supply networks to withstand disruption.

Sustainability is a core strategic driver in roquettes farm operations and sourcing. Roquette leads with plant based excipients and eco efficient manufacturing, supporting a shift towards bio based circular supply chains, products such as ready lie code showcase how green innovation can meet both performance and environmental targets, and our company applies science based metrics and transparent Supply partnerships to help customers track and achieve ESG goals.

Yeah, cphi 2025. Is extremely exciting for Roquette. It marks the debut of roquettes unified health and pharma Solutions Group, and this is a milestone following the qualicaps and IFF pharma solutions, acquisitions and integrations. So we'll be there displaying under the banner united for better health, and Roquette will showcase our combined strength and excipients, APIs, drug delivery technologies and unique customer service. Our company looks forward to engaging in key industry themes such as AI, sustainable manufacturing, biopharma innovation and resilient supply chains, and it's really a great opportunity to demonstrate how three legacies have united to deliver faster, safer, more effective and more sustainable therapies for customers and patients.