Pharmaceutical Technology-03-02-2008

Pharmaceutical Technology

There are significant differences between the United States and European Union requirements for the annual review of records related to the manufacturing and control for pharmaceutical products and active pharmaceutical ingredients.

Pharmaceutical Technology
Washington Report

March 02, 2008

Quality-by-design submissions may reduce supplements and improve change management.

Pharmaceutical Technology
Viewpoint

March 02, 2008

After two centuries, there's no reason to maintain two tablet compression tooling standards.

News
Pharmaceutical Technology

March 02, 2008

A. Nair discusses patent disputes in India.

Agent-In-Place
Pharmaceutical Technology

March 02, 2008

If not properly monitored, filters and plastic bags can keep back more than they should.

Pharmaceutical Technology

New packaging options monitor and protect temperature-sensitive products.

Inside USP
Pharmaceutical Technology

March 02, 2008

The United States Pharmacopeia emphasizes mechanical calibration and a performance test to esnure integrity of the dissolution procedure.

Pharmaceutical Technology

The pharmaceutical industry plans moderate increases in spending for equipment and machinery in 2008. Investments include equipment for solid-dosage manufacturing, active pharmaceutical ingredients, and parenteral manufacturing.

Mannitol is the most commonly used bulking agent in freeze-drying formulation design. The benefit of using mannitol is that it crystallizes during freezing and permits drying processes at higher product temperatures, and thus with higher sublimation rates relative to purely amorphous systems (1). Mannitol, however, is known to form different crystalline modifications which compromises reproducibility of product characteristics and storage stability due to phase transformations (2, 3).

Pharmaceutical Technology

New research and ideas for March 2008

Pharmaceutical Technology
PharmTech Talk

March 02, 2008

Contract manufacturers of APIs and intermediates are cautiously optimistic.

Pharmaceutical Technology
Special Report

March 02, 2008

Chemical imaging of solid dosage forms has become a powerful analytical tool for the development of solid dosage forms.

Pharmaceutical Technology

Using a handheld Raman spectrometer, the authors developed methods for 28 commonly used excipients and active ingredients.

Online Exclusive
Pharmaceutical Technology

March 02, 2008

SAFC is delivering on its plan for double-digit annual growth by increasing its businesses through organic growth and targeted technology acquisitions.

Pharmaceutical Technology
Peer-Reviewed Research

March 02, 2008

The selection of an appropriate salt form for a potential drug candidate is an opportunity to modulate its characteristics to improve bioavailability, stability, manufacturability, and patient compliance.

Pharmaceutical Technology
In the Spotlight

March 02, 2008

Editors' Picks of Pharmaceutical Science & Technology Innovations; Analytical system provides multiuser capability; Encapsulator aids dosage design; Versatile drive offers quick setup

Pharmaceutical Technology
Ingredients Insider

March 02, 2008

The European Union's REACH initiative has the potential to affect the flow of chemicals into the pharmaceutical suppy chain.

Pharmaceutical Technology

Show blasts off this month in Philadelphia with more suppliers, new trends, and real-world solutions.

Pharmaceutical Technology
Special Report

March 02, 2008

Results from Pharmaceutical Technology's Equipment and Machinery Trends survey and industry members provide insight into product innovation

Pharmaceutical Technology

CMOs have positive outlook for 2008 but are wary of competitive pressures.

Online Exclusive
Pharmaceutical Technology

March 02, 2008

A preview of some product enhancements and launches for Interphex 2008, the large trade show being held Mar. 26–28 in Philadelphia.

Pharmaceutical Technology
News

March 02, 2008

A news roundup for March 2008.

In this topical review, the authors discuss the rationale behind microstructural requirements for biopharmaceutical equipment and problems that may be encountered during the fabrication of high-performance corrosion-resistant equipment.

Pharmaceutical Technology
Pharma Capsules

March 02, 2008

Brief pharmaceutical news items for March 2008.

Pharmaceutical Technology

This article focuses on upgrading and improving a packing process to comply with current good manufacturing practices. The authors sought to maintain proper quality assurance for finished products.