Pharmaceutical Technology-10-02-2001

Pharmaceutical Technology

Outsourcing Outlook

October 02, 2001

Contract Services

25

10

Recovery of the contract services industry picked up steam in the quarter ending 30 June 2001.

Effects of Polyethylene Glycol on Morphology, Thermomechanical Properties, and Water Vapor Permeability of Cellulose Acetate-Free Films

October 02, 2001

Articles

25

10

The authors provide a systematic evaluation of the effects of solvent systems, PEG molecular weight, and concentration of CA to PEG on the thermomechanical properties and permeabilities of CA-free films.

Hydrogels for the Controlled Release of Pharmaceutical Proteins

October 02, 2001

Articles

25

10

Two types of hydrogels used in parenteral protein-delivery systems offer opportunities for achieving a variety of prolonged- and delayed-release patterns.

Near-Infrared Inspection Complements Other QC Systems

October 02, 2001

Columns

25

10

NIR quality control technology, relatively new to the pharmaceutical industry, could revolutionize processing and packaging.

Safety and Manufacturing Standards

October 02, 2001

Columns

25

10

FDA may adopt new requirements to enhance the safe use of pharmaceuticals and ensure that all US drugs are available when needed.

Qualification of Network Components and Validation of Networked Systems, Part I

October 02, 2001

Articles

25

10

Part I of this article discusses validation plans, FDA expectations, and specific requirements for the validation of networked systems.

System Optimization for In Situ Fiber-Optic Dissolution Testing: Hydrodynamic Effects, System Performance, and Applications

October 02, 2001

Articles

25

10

Testing of an in situ fiber-optic transmission probe demonstrates sound hydrodynamic performance and reduced stray-light limitations.

Current Status of the Oral Delivery of Insulin

October 02, 2001

Articles

25

10

Insulin is one of the most popular proteins to be studied for oral delivery. The authors review the current status of the development strategies of insulin drug delivery systems, the various challenges associated with these systems, and how these challenges may be overcome.

Laboratory Equipment Qualification

October 02, 2001

Articles

25

10

A summary of the conclusions of the PhRMA Workshop on Acceptable Analytical Practices describes equipment qualification practices and guidelines that are designed to help the pharmaceutical industry be consistent in meeting core requirements.

Filter Integrity Testing in Liquid Applications, Revisited, Part I

October 02, 2001

Articles

25

10

In Part I of this article, the authors summarize the principles of various integrity tests, including their performance and purpose.

360&#176 Feedback &#45 Improving the Selection Process All the Way Around

October 02, 2001

Contract Services

25

10

Evaluating a CRO should involve acquiring feedback from various personnel within the CRO, ranging from executives to line workers.

Entering into an Alliance with Big Pharma: Benchmarks for Drug Delivery Contract Service Providers

October 02, 2001

Contract Services

25

10

The author proposes a strategy for achieving a successful partnership with Big Pharma on the basis of forming a relationship with the company, deliberately managing the alliance, and clearly defining roles and responsibilities.