Equipment

Boreas from Telstar are -86 ºC ultra-low-temperature freezers developed to house COVID-19 vaccines.

The new Sanitary Rotary Batch Mini Mixer from Munson Machinery Company has the ability to de-agglomerate and blend up to 5 ft3 (142 ℓ) of dry bulk ingredients with or without liquid additions at several locations.

ROSS’ Sanitary Ribbon Blenders with ergonomic material handling accessories feature a new design that allows operators to safely empty bags of powder through a bar grating while an adjacent vibrating tray assembly catches debris and off-spec ingredients.

Cytiva’s new facility in Shrewsbury, MA will make equipment such as single-use bioreactors.

The company is investing in expansion at four sites in the United States, United Kingdom, and Italy, which will include construction of new facilities and addition of sterile and lyophilized filling lines.

The investment will expand and upgrade manufacturing capacity and technology for pre-fillable syringes and will also includes a new manufacturing facility in Europe.

The Double Planetary Mixer from ROSS is suitable for high-precision mixing, granulation, and vacuum drying all in one.

Gerresheimer now offers its Gx RTF syringes with SG ITC (Integrated Tip Cap) twist-off closure from Stevanato Group.

ACG Group introduced the GT 1600 X.ONE, a line of integrated granulation equipment designed for high-volume batch production.

The IsoAir Pro-E Remote Particle Counter by Particle Measuring Systems works to streamline cleanroom monitoring while complying with global regulations.

Pharmaceutical Technology spoke with Tania Pereira Chilima, Deputy CTO at Univercells Technologies about their technology and how it can be used in viral vector manufacturing, which is needed for production of some of the COVID-19 vaccine candidates.

A holistic approach to validation and quality assurance is essential.

The expansion will include a new 25,000-ft2 warehouse, a filling line for flexible plastic containers, a high-speed automated syringe fill line with the ability to fill up to 600 units per minute, and a high-speed automated visual inspection line.

The new super plant, being built in Incheon, South Korea, will have a total biopharmaceutical manufacturing capacity of 256,000 L.

The agreement follows a recent announcement that Sartorius plans to invest $100 million in Songdo, South Korea’s bio cluster.

The 110,000 ft2 site, which is set to be operational by the second half of 2021, will feature new technology including 2000-L scale bioreactors and additional fill-finish capabilities.

Sanofi’s Digitally Enabled Integrated Continuous Biomanufacturing Facility in Framingham, MA was named the Overall Award winner at the ISPE virtual annual meeting.

TurboFil Packaging Machines introduced the SimpliFil Syringe Filling & Assembly System for the automated production of syringe formats.

The ROSS Double Planetary Mixer from Charles Ross & Son Company is available with an optional weighing system for precise measurements throughout the batching procedure.

The HFC Disconnect Series from CPC (Colder Products Company) provides sterile disconnection of tubing used for single-use biopharma and cell and gene therapy manufacturing systems.

The new line of Defined Tubing Routing (DTR) from High Purity New England is a flexible tubing support system for single-use biopharmaceutical manufacturing.

Two FDA-funded projects at RCPE will look at real-time monitoring and control of drug tablet coating and developing a digital twin for drug production control.

The CountQ system from Verista automates accurate counts of tray-loaded parts, including vaccine vials.

Automation, digitalization, and supply-chain strategies help mitigate vulnerabilities in both autologous and allogeneic cell therapy manufacturing.

Rigaku is featuring its latest x-ray instrumentation at three virtual booths at the virtual 27th International Trade Fair for Laboratory Technology, Analysis, and Biotechnology conference.

The facility will include a high-speed sterile line for live virus filling, a line for standard fill/finish, cleanroom capacity, labs, warehousing, and offices to support production.

The new facility at the company’s San Diego, CA, site will be for late phase and commercial CGMP manufacturing.

Cytiva will provide the first FlexFactory to be used in the manufacture of pDNA to Akron Bio.

The manufacture of gene therapy vectors is shifting to more modern technologies.

Facility and equipment design are important, but the team and its experience matter most.