Consider a matrix of factors when choosing the type of cleanroom facility.

Cleanroom Infrastructure Choices

Advanced analytics reveals process insights.

Optimizing Tech Transfer

Technology protects the supply chain from manufacturer to patient.

Countering Counterfeiters and Diverters

Expert help is crucial for drug sponsors that design their own facilities.

Best Practices for Building a Pharma Facility

Topic

Articles

The expansion, to be completed in April 2021 aims to increase the CDMO’s viral-vector production capacity in Spain.

VIVEbiotech to Expand Facilities for Lentiviral-Vector Manufacturing

Alex Bunting is marketing manager at I Holland

Understanding difficulties that can occur during manufacture and resolving them quickly can improve oral solid-dosage drug production.

Troubleshooting Problems Affecting Tooling During Tablet Manufacture 

Aprecia's compression-free 3DP manufacturing platform and Glatt’s multiparticulate technologies offer solutions to pharmaceutical dosage design challenges.

Glatt and Aprecia Collaborate on 3D-Printing for Solid-Dosage Drugs

The second phase of the Myford facility expansion in California will add upstream and downstream processing suites.

Avid Bioservices Expands Biologics Manufacturing Capacity

The deal expands Wavelength’s drug substance manufacturing footprint and its API CDMO business.

Wavelength Pharmaceuticals Acquires Vanamali Organics

Through the agreement, Catalent will manufacture LUPKYNIS (voclosporin), Aurinia’s drug for the treatment of adult patients with lupus nephritis, at its pharmaceutical softgel center of excellence in St. Petersburg, FL.

Catalent Announces Multi-Year Supply Agreement with Aurinia Pharmaceuticals

Cascade began production on new facilities to manufacture APIs for clinical and commercial GMP production.

Cascade Chemistry Expands API Manufacturing Capacity

The companies have expanded their existing partnership to include 40 Million Doses of COVID-19 vaccine for South Korea.

Novavax Expands COVID-19 Collaboration and License Agreement with SK Bioscience 

The acquisition will integrate drug substance, drug product, and clinical testing capabilities under Quotient.

Quotient Sciences Acquires CDMO Arcinova

Integration of Brooks Life Sciences BioStore III automated storage and inventory monitoring solution with Cytiva’s Chronicle software will improve traceability, process control, and monitoring capabilities.

Cytiva Integrates Brooks Life Sciences Automated Cold Chain Storage Platform

Jennifer Markarian is manufacturing editor of BioPharm International.

Collaboration between equipment suppliers and users is leading to innovation and optimization in biopharmaceutical manufacturing.

Optimizing Bioprocessing Equipment to Speed Development and Increase Capacity

Hallie Forcinio is BioPharm International's packaging editor, editorhal@sbcglobal.net

Labeling, printing, and on-dose tagging technologies provide a multi-layered approach to anticounterfeiting for pharmaceuticals.

Counterfeiting Countermeasures

Evonik has revealed plans for investment in the short-term expansion of its specialty lipids production, which are used with mRNA-based COVID-19 vaccines. 

Evonik Invests in Additional Lipid Production for mRNA-based Vaccines

The companies will build capacity in Germany that will be ready in 2022 and are exploring options for increasing volume in 2021.

AstraZeneca and IDT Biologika Plan Vaccine Capacity Expansion 

Videos

Lessons learned from the pandemic can advance future biologic drug development and manufacturing.

Pandemic Response Lessons

How can artificial intelligence and machine learning be used to gather and process real-time manufacturing data? 

Employing AI and Machine Learning to Advance Process Operations

The company recently installed a fully validated visual inspection system that uses artificial intelligence in an automated inspection machine.

Syntegon Validates First AI-Equipped Visual Inspection System in Production Line

The CGMP manufacturing agreement will expand production of lenzilumab, a candidate for COVID-19 therapy, to support a potential emergency use authorization filing.

Avid Bioservices Enters Manufacturing Agreement with Humanigen for Lenzilumab

As demand for COVID-19 vaccines increases, Big Pharma offers its manufacturing capacity and expertise.

Big Pharma Takes on Vaccine Production

Eric Sanchez is a senior consultant of Integra Continuous Manufacturing Systems with a special focus on the implementation of continuous manufacturing methods. He joined the firm after a successful 31-year career with Janssen Pharmaceuticals.

Fernando J. Muzzio, PhD, is distinguished professor of the School of Engineering at Rutgers, The State University of New Jersey, Piscataway, NJ 08855. Dr. Muzzio is a member of 

 editorial advisory board and President of Integra Continuous Manufacturing Systems.

Advanced manufacturing technologies are available, but challenges need to be addressed.