Capsugel's Bram Baert and Sandrine Picco argue that chasing zero nitrite in pharmaceutical excipients is often impractical and costly. They recommend setting scientifically justified, risk-based limits and consistently staying below them.
News|Articles|December 2, 2017
- Pharmaceutical Technology-12-02-2017
- Volume 41
- Issue 12
Oven Autosampler for Automated KF Titration
The InMotion Karl Fischer (KF) Oven Autosampler from Mettler Toledo is suited for KF titration and comes in two models, InMotion Flex and InMotion Pro, and allows up to 26 samples to be analyzed on a 25-centimeter platform.
The InMotion Karl Fischer (KF) Oven Autosampler from Mettler Toledo is suited for KF titration and comes in two models: InMotion Flex and InMotion Pro. Features include a vial with a one-piece screw cap for sample preparation safety, an automatic gas flow meter for gas flow control, and a temperature scan function that can determine a substance’s ideal heating temperature in one run containing up to 120 samples without stopping, according to the company.
The instrument allows up to 26 samples to be analyzed on a 25-centimeter platform. The Pro model offers three platforms and vial size, with customizable sizes available. The procedure calibrates both the oven temperature and the gas flow rate to the titration cell, complying with current Official Medicines Control Laboratory (OMCL) guidelines (Qualification of Automatic Titrators, 2016). Details are documented with certificates, and the company provides service and support throughout the product’s entire lifecycle. Additionally, both models connect to the latest versions of the company’s Volumetric (V30S) and Coulometric (C30S) KF Titrators, as well as to the modular T7 and T9 Excellence Titrators.
Articles in this issue
almost 9 years ago
Disputes Over Manufacturing Waiver and Other SPC Exemptionsalmost 9 years ago
Opportunities with Softgelsalmost 9 years ago
What’s in Your SOP?almost 9 years ago
Transformative Medicines Challenge FDA and Manufacturersalmost 9 years ago
Pharma Outsourcing: A Year in Reviewalmost 9 years ago
Outsourcing: A Year in Reviewalmost 9 years ago
Designing Sustainable Pharma Facilitiesalmost 9 years ago
Evaluating Surface Cleanliness Using a Risk-Based Approachalmost 9 years ago
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