Shimadzu's New Spectrophotometer Enhances Usability, Performance, and Compliance

Pharmaceutical Technology's In the Lab eNewsletter

In the Lab eNewsletter, Pharmaceutical Technology\'s In the Lab eNewsletter-06-07-2018, Volume 13, Issue 6

The company’s new UV-1900 UV-VIS spectrophotometer incorporates features that improve usability, regulatory compliance, and performance.

Shimadzu Scientific Instruments’ (SSI’s) new UV-1900 ultraviolet–visible spectroscopy (UV-VIS) spectrophotometer incorporates technically advanced features that improve usability, regulatory compliance, and performance. The instrument can used for analytical purposes in foods, pharmaceuticals, life sciences, chemistry, and electronics.

The spectrophotometer offers ease-of-use operation because it is equipped with a high-visibility color touch panel that users can control with a finger or a stylus pen. The on-screen user interface includes large, easy-to-see icons on a black background, making the instrument settings evident at a glance. Operation is simplified with the navigation, and the user interface minimizes transitions between windows. In quantitation mode, the stages of the entire measurement process and the current status are shown on the display, allowing users to prepare for the next step. The control panel is ergonomically designed to provide an optimal viewing angle.

The instrument has new validation functions that are compliant with United States Pharmacopeia and the European Pharmacopeia. It can also run checks for nine Japanese Industrial Standards items and the Japanese Pharmacopoeia. Operators can save checked conditions and results and easily refer to them as needed. The instrument supports database management, user authority management, and data audit trails for compliance with FDA 21 CFR Part 11, Pharmaceutical Inspection Convention and Pharmaceutical Inspection Co-operation Scheme GMP guidelines, and other electronic records and electronic signatures regulations.

The instrument's ultra-fast scan performance makes it capable of obtaining high-accuracy spectra in a few seconds. It has a photometric repeatability accuracy of 0.0002 Abs max. (0.5 Abs and 1.0 Abs), a five-times improvement over conventional performance levels. This high photometric repeatability accuracy reduces variance in measurement results and enables more accurate quantitation and detection of low-concentration samples. The photometric range of -4 to 4 Abs and the 0.5 % max. (198 nm) reduction of stray light provides accurate measurements of high-absorbing samples. Measurement modes include photometric, spectrum, quantitation, kinetics, time course, and biomethod.

Next-generation LabSolutions UV-Vis software has also been released in conjunction with the instrument. The software features a simple design layout that enables easy operation performance even for first-time users. Functions such as data transfer to spreadsheet software and batch text export of multiple data sets significantly enhance the efficiency of routine analysis, according to the company.

Source: Shimadzu