Fluid-Bag Ltd provides comprehensive 900 and 1000 litre flexible IBC systems for liquid and semi-solid products, including filling and discharging equipment. The GMP compliant container system is designed to guarantee uniform liquid, maximise payload and minimise discharge residue (0.5% residue).
Pharmaceutical Technology Europe
The physical form of an API is an important consideration in formulation development. Particle-engineering technologies, such as crystal design for controlling crystallisation and producing cocrystals, particle-size reduction and amorphous solid dispersions, help to optimise delivery of a drug.
Pharmaceutical Technology Europe
The advantages and disadvantages of hot-melt extrusion in solid dispersion formulations.
The authors describe a solid form technology platform used to optimize salt selection, cocrystallization identification and modification, or the development of a free form.
Pharmaceutical Technology Europe
Rob Blanchard and Clive Roberts discuss the issues surrounding tablet sticking.
In addition to the established coating systems (like the BFC and the BFC TriPan), Bohle developed a new coater to face the market needs, the Bohle-Tablet-Coater BTC.
New coating technologies achieve high uniformity and reduce waste through mixing system advances and pan and airflow configuration.
A technical forum featuring Tim Freeman of Freeman Technology and Carl Levoguer of Malvern Instruments.
As part of an ongoing collaboration into tabletting science, I Holland and the UK's University of Nottingham have launched a two-year programme to investigate the cause of tabletting sticking.
Equipment and Processing Report
In our tablet coating process, we are losing up to 15% of our coating solution in each processing run. What can we do to prevent this problem in order to reduce waste and increase our cost efficiency?
This article considers the different conditions to which the powder is subjected in the tableting process, and discusses which powder properties should be measured to accurately reflect likely powder behavior in the process.
Experts in solid dosage discuss the formulation and manufacture of multilayer tablets.
Industry experts discuss formulation and technical challenges in multilayer tablet manufacture.
This risk-management case study focuses on assessing empty capsules.
A Q&A with Joe Cascone, director of potent pharmaceutical development at Metrics, moderated by Patricia Van Arnum. Discussion of the key considerations made in facility design, equipment selection, and operations to achieve desired levels of containment.
Xevo TQD provides ultimate consistency between analyses; instrument to instrument, lab to lab; both the advanced technology of the ACQUITY UPLC System and the robust universal ion source architecture on the Xevo TQD guarantee flexibility and dependability.
Equipment and Processing Report
Filling active ingredients directly into capsules is probably the quickest option for entering clinical trials. This case study compares manual and automated methods of capsule filling.
The aim of this study was to prepare and characterize physiochemically and biologically tamoxifen-loaded SLNs to evaluate their effectiveness as a drug-delivery system to treat breast cancers.
Pharmaceutical Technology Europe
Pharmaceutical Technology Europe brings together suppliers of tabletting equipment and excipients to discuss the challenges, innovations and latest trends in the tabletting industry.
The authors evaluated the manufacturing data of 40-mg tablets of furosemide, a potent diuretic.
A single, global tooling standard would offer many benefits, but one has been slow to emerge.
FDA issued a draft guidance for industry on Jan. 18, 2011, about the size of beads within drug products labeled for sprinkle.
The authors describe an alternative approach to compressing and coating minitablets for use in a sustained-release, solid oral-dosage form. This article is part of a special Drug Delivery issue.
The author outlines how to choose carriers and capsule shells according to dosage requirements and intended use. This article is part of a special Drug Delivery issue.
Pharmaceutical Technology Europe
Granulation is the most crucial step in the manufacture of solid dosage forms.
