Kill the Bioburden, Not the Biological Indicator

Pharmaceutical Technology, Pharmaceutical Technology-05-15-2017, Volume 2017 eBook, Issue 1
Pages: s47-s50

Understanding the purpose of the biological indicator can guide the development of an effective sterilization process.

The PNSU, probability of a non-sterile unit, is crucial to determining process conditions.  However, the concept is often misapplied. 

Sterile processing expert Jim Agalloco explains how the proper application of a biological indicator can guide the development of an effective sterilization process.
 

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