Kill the Bioburden, Not the Biological Indicator

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Pharmaceutical TechnologyPharmaceutical Technology-05-15-2017
Volume 2017 eBook
Issue 1
Pages: s47-s50

Understanding the purpose of the biological indicator can guide the development of an effective sterilization process.

The PNSU, probability of a non-sterile unit, is crucial to determining process conditions.  However, the concept is often misapplied. 

Sterile processing expert Jim Agalloco explains how the proper application of a biological indicator can guide the development of an effective sterilization process.
 

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Articles in this issue
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Clean, Disinfect, and Validate
Bioburden_225-1.jpg
Kill the Bioburden, Not the Biological Indicator
Cryoport_225.jpg
Cold Chain Logistics for Personalized Medicine: Dealing With Complexity
RawMaterials_225.jpg
Ensuring the Biological Integrity of Raw Materials
TechTransfer_225.jpg
Getting Biopharmaceutical Tech Transfer Right the First Time
Vetter_225.jpg
Developing an Injectable Compound for a Dual- Chamber Delivery System
GSK_225.jpg
Case Study: Retrofitting Two New High-Purity Water Systems
SUBioreactors_225.jpg
Single-Use Bioreactors Have Reached the Big Time
ParallelProcessing_225.jpg
Parallel Processing
Biosims_225.jpg
Cost Considerations Drive Lean Technology in Biomanufacturing
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