Solid/Semi-Solid Dosage

Raman spectroscopy delivers real time, non-destructive process insights for critical process parameters to monitor pharmaceutical manufacturing.

Manufacturers of oral solid dose pharmaceutical formulations need PAT tools to reduce a product’s time-to-market and increase profitability.

Tests evaluated commercial rotary tablet presses to see how effectively they deal with problems such as poor flow, overlubrication, and capping.

Dosage-level authentication provides an added digital layer of security for pharmaceutical companies to ensure their products are not exposed to falsification.

Aprecia's compression-free 3DP manufacturing platform and Glatt’s multiparticulate technologies offer solutions to pharmaceutical dosage design challenges.

Advanced manufacturing technologies are available, but challenges need to be addressed.

The films are now available in three options of varying thickness for added protection against moisture and oxygen.

This paper reviews considerations for the formulation of chewable tablets including sensory characteristics, chewability assessment, and drug release.

Amorphous solid dispersions are a useful tool in overcoming solubility issues, but they have not yet reached full potential in commercial success.

Two FDA-funded projects at RCPE will look at real-time monitoring and control of drug tablet coating and developing a digital twin for drug production control.

The new premix can be used with tablets and a range of other solid oral dosage forms.

The OneXpress solution is designed to accelerate oral dosage drug development and manufacturing.

Early adopters and equipment manufacturers refine their equipment and processes, paving the way for broader use.

Early adopters and equipment manufacturers refine their equipment and processes, paving the way for broader use.

Data and software identify optimum pharmaceutical packaging choices for the required shelf-life.

Using a specific addition method to wet the powder bed in twin-screw granulation using a foam binder improves robustness for continuous solid-dosage drug product manufacturing.

The continuous manufacturing platform can be used for individual unit operations or a complete solid-dosage manufacturing line and can be integrated with third-party equipment.

The correct mix of excipients is crucial to the success of fast dissolving/orally disintegrating dosage forms.

A quick look at the history of OTC dosage form development shows the importance of patient-centered innovation.

Risk levels should be considered when designing containment for pharmaceutical tableting equipment to enhance operator safety.

Understanding formulation properties early in development can prevent some costly issues later on.

OSD forms are popular within the industry due to the various advantages they offer, but there are specific considerations required to get the best OSD form possible.

This article examines multi-tip tool technology for pharmaceutical tablet compression and the process control and validation issues that must be carefully evaluated to assess the potential for success.

Tools help improve understanding of excipient risk in formulating OSD drugs.

Understanding European GMPs and new rules from China for excipients are crucial for formulating solid-dosage drugs.