Solid/Semi-Solid Dosage

To achieve the maximum performance from a tablet press run, operators must learn to distinguish between machine-related issues and granulation-related issues.

Tablet manufacturers often overlook critical basic concepts or established practices. The author draws from his own experiences and discusses how solid dosage manufacturers can improve production and product quality by optimizing major unit operations.

The authors modified a three-layer press to operate a compression-coated tablet process that may offer several advantages over tradditional compression coating operations.

The author assesses the compressibility of Plasdone S- 630 copovidone-based tablet formulations using roller-compaction and direct-compression processes.

This comparative study suggests that pregelatinized starches are superior to natural starches in terms of improving the plastic deformation in tablet formulations during compression.

This study attempts to determine the combination of excipients found in commercial ASA products that would be suitable for use in an aqueous enteric film&#173coating process.

Both academia and industry have been encouraged to generate quick&#173dissolving dosage forms as the demand for fast&#173disintegrating tablets and capsules has steadily increased.

Appropriate sampling procedures, proper preparation, and correct instrumental parameters may yield differing, but correct, results.

Evolution of an existing drug molecule from a conventional form to a novel delivery system can significantly improve its performance in terms of patient compliance, safety, and efficacy. These days,drug delivery companies are engaged in the development of multiple platform technologies to get competitive advantage, extend patent life, and increase market share of their products.